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Introduction
As the crypto market regains momentum in the second half of 2025, mid-cap “blue-chip” projects are emerging as prime opportunities for investors seeking strong fundamentals with high upside potential. These are well-established protocols with proven use cases, active communities, and room to grow. From DeFi and Layer-2 solutions to AI and Web3 infrastructure, the following 10 projects stand out for their innovation, adoption, and strategic positioning. This list explores what each project does, why it matters now, and what could drive significant returns by year-end.
6/10/2025, 6:09:20 AM